21cfr pollen raw material expiry dating

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Do not administer in the presence of diseases characterized by bleeding diathesis.Individuals with autoimmune disease may be at risk of exacerbating symptoms of the underlying disease, possibly due to routine immunization.Respiratory obstruction not responding to parenteral or inhaled bronchodilators may require theophylline, oxygen, intubation and the use of life support systems.

Sensitive patients may experience severe anaphylactic reactions resulting in respiratory obstruction, shock, coma and/or death.Food extracts made from dried raw material are extracted at 2-10% (- w/v ratio) in extracting fluid containing 50% glycerine.Slurries of juicy fruits or vegetables (prepared with a minimum amount of water for injection) are combined with an equal volume of glycerine for a ration of 1:1 volume/volume (v/v).The routes of administration for diagnostic purposes are intradermal or prick-puncture of the skin.FOR ALLERGENIC EXTRACTS CONTAINING 50% V/V GLYCERINE AS PRESERVATIVE AND STABILIZER: Sodium chloride…………………………………………………………….0.95% Sodium bicarbonate………………………………………………………..0.24% Glycerine…………………………………………………………………50% (v/v) Water for Injection…………………………………………………q.s.

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